Cancer research is rather important, and there is no doubt that scientists are doing what they can in order to better understand what happens with the cells in our bodies in such conditions, as well as how to, of course, target them better and what to do in order to prevent them from growing and developing. Of course, in addition to simply finding ways to kill cancer cells, scientists are now studying those pathways and signaling processes that actually result in the proliferated growth, in an effort to target the pathways specifically, and test new therapeutic strategies.
One of their targets is, of course, the FAK, that is, the Focal Adhesion Kinase, which is basically an enzyme that has great implications in cancer progression, cancer stem cell maintenance, as well as metastasis. And, VS-4718, which is also known as PND-1186, appears to be a rather useful tool in the process of targeting this specific enzyme, and preventing it from doing its work, and from, thus, sending those growth signals to tumor cells. In short, it is a potent, as well as a selective, FAK inhibitor.
The fact that you are here tells me a few things about you. Sure, those are just assumptions, and I could be wrong, but let me have a go. First things first, it tells me that you are a researcher yourself, whether a seasoned or a new one, or at least that you want to be one, and that you are, therefore, interested in understanding some cancer-related things much better.
Then, it also tells me that you are specifically interested in one particular thing. That is, in figuring out where to get VS-4718 (PND-1186) FAK inhibitor for your research. Because, after all, you know that you cannot exactly get it at a local pharmacy. And, since that is not an option, you want to learn what is, which is what we are going to be talking about below in more details.
Not before we ensure that you understand what VS-4718 (PND-1186) FAK inhibitor actually is, though. Because, there would be no point in getting it for your research if you don’t really have a clue about what it is and how it works. Of course, I am assuming that you do have some knowledge about this already, but let us not risk it, and let us quickly recap what you have to know about this drug.
What Is VS-4718 (PND-1186) FAK inhibitor?
So, in few words, VS-4718 (PND-1186) FAK inhibitor is actually a small molecule drug that works to inhibit FAK. Its effects are reversible, that is, it binds non-covalently, and it is selective for FAK specifically. And, since FAK is crucial for certain processes, such as cell adhesion, invasion, motility, survival, as well as cancer stem cell regulation, it is no wonder that this particular drug is so important in cell biology and cancer research.
Basically, the drug works by binding to the active region of FAK, or near it, thus preventing downstream signaling. When the activity of FAK is blocked, thus, those survival signals, as well as growth signals are disrupted, which can lead to cell cycle arrest, apoptosis, as well as the reduced motility and invasion of cells. In short, thus, this can inhibit tumor growth and suppress metastasis. VS-4718 (PND-1186) FAK inhibitor can be dosed orally, or by injection, and another one of its great traits is that it can actually prevent relapses post chemo, in preclinical breast cancer models.
Here’s more on targeting FAK: https://www.mdpi.com/1422-0067/23/4/1998
How Can You Get It?
Okay, the above should have given you a better idea about what this drug is and how it works. Just in case you weren’t already familiar with it. If you are a researcher, though, then I suppose you know much more than what has been said above already, and that you are interested in finding out even more, which is definitely a good thing, because it means that we may see some new developments in the treatment of cancer due to your research. In any case, to be able to research VS-4718 (PND-1186) FAK inhibitor, you will have to, well, first get it for your lab.
And, as I have hinted at above, the idea of getting it at a pharmacy is not a good one. In short, that is impossible. That, however, does not mean that there is no other way, and that you won’t be able to get it at all. The good news is that there are a lot of suppliers catering specifically to research labs, and thus allowing you to get the substances you need for your studies and experiments. And, you will get VS-4718 (PND-1186) FAK inhibitor by connecting to those suppliers specifically.
Of course, you will have to take some time to choose the right supplier for yourself. Before we get to that, though, let me give you a useful piece of information and get you familiar with something that will definitely make things much less complicated. In short, you can nowadays find these suppliers online, which allows you to complete the purchasing process much more easily.
How to Choose a Supplier?
Now, if you have gotten some recommendations from the people you know, or you have done some searching of your own, you may have come across a few suppliers that can sell VS-4718 (PND-1186) FAK inhibitor to you. Yet, you know better than to randomly select one or the other. Instead, you want to understand specifically how you should make this choice – that is, what it is that you should take into account when trying to make a good one. So, let me tell you a bit more about that.
First off, check the purity of the drug they are selling, and don’t settle for low quality, since impurity can confound your results. Then, check batch consistency, because you want them all to behave the same. Of course, read some reviews to check the reputation of particular suppliers, and don’t forget to also check the prices and compare them, at the same time ensuring that you’re planning your budget perfectly, so as to get precisely what you need.